MARROW CELLUTION
Solution for Regenerative Medicine
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MARROW CELLUTION® is the only product in the Brazilian market that extracts bone marrow with material richness of 80% of marrow and 20% of peripheral blood, which allows the application without the use of centrifugation or any method of purification of the extracted material
TECHNOLOGY AND DIFFERENTIALS OF MARROW CELLUTION
• Exclusive product in Brazil;
• Suction cannula with side holes;
• No need for centrifugation or filtration;
• On-site rotation technology;
• Higher amount of extraction of mesenchymal cells;
• Eliminates risk of contamination and material exchange.
PATIENT BENEFITS
• Minimally invasive technique;
• Inhibits contamination of the extracted material;
• Decreased inflammatory process;
• Restitution of functional capacity;
• Decreased regeneration time;
• Decrease in hospital hotels;
• Inhibits the formation of fibrosis.
APPLICATION AND USES
Proven effectiveness in Orthopedic, Oral-Maxillofacial and spine surgeries, as well as in the treatment for the elderly and in sports medicine. It can be successfully used along with bone grafts, cartilages, grafts of all kinds, in various surgical procedures, mainly:
• Pain Relief
• Arthritis
• Osteoarthritis
• Tendinopathies
• Ligament injuries
• Disc degeneration
• Arthrodesis
• Pseudoarthrosis
• Bone necrosis
• Prostheses
• Maxillary reconstruction
• Orthognathic
• Fractures
REGENERATIVE THERAPY AND SPORTS MEDICINE
Regenerative Medicine explores the patient’s own capacity for regeneration, using mechanisms of signaling, cellular differentiation and replication with an impact on organs and tissues to restore or establish their original function. One of the most promising techniques is the use of bone marrow aspirate (BMA), a technique that has been explored by Sports Medicine, aiming to increase the speed and efficiency in the regeneration of damaged tissues and organs, to enable the reintegration of the athlete to their sporting activities.
SCIENTIFIC STUDIES
1 J Maxillofac Oral Surg. 2017 Mar;16(1):71-78. doi: 10.1007/s12663-016-0924-4. Epub 2016 Jun 10. Autogenous Bone Marrow Aspirate Coated Synthetic Hydroxyapatite for Reconstruction of Maxillo-Mandibular Osseous Defects: A Prospective Study. Gali RSI, Devireddy SK1, Mohan Rao N2, Kishore Kumar RVI, Kanubaddy SRI, Dasari Mi, Sowjanya K1, Pathapati RM3.
2 Foot Ankle Clin. 2016 Dec;21(4):839-845. doi: 10.1016/j.fcl.2016.07.005. Bone Marrow Aspirate Concentrate for Bone Healing in Foot and Ankle Surgery. Harford JSI, Dekker TJ1, Adams SB2.
3 Orthop | Sports Med. 2016 Jan 13;4(1):2325967115625481. doi: 10.1177/2325967115625481. eCollection 2016. Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the knee: A Systematic Review of Outcomes. Chahla J1, Dean CS1, Moatshe G2, Pascual-Garrido (3,Serra Cruz R4, LaPrade RF5.
4. Int Orthop. 2014 Sep;38(9):1845-53. doi: 10.1007/s00264-014-2342-x. Epub 2014 Apr 13. Percutaneous grafting with bone marrow autologous concentrate for open tibia fractures: analysis of forty three cases and literature review. Le Nail LR1,Stanovici J, Fournier J, Splingard M, Domenech J, Rosset P.
5 J Craniomaxillofac Surg. 2017 Jan 12. pii: S1010-5182(17)30007-0. doi: 10.1016/j.jcms.2017.01.007. The role of bone marrow aspirate cells in the management of atrophic mandibular fractures by mini-invasive surgical approach: Single-institution experience. Mannelli G1, Arcuri F2, Conti M2, Agostini T2, Raffaini M2, Spinelli G2.
6 Int J Spine Surg. 2016 Oct 17;10:35. eCollection 2016. Outcomes of Demineralized Bone Matrix Enriched with Concentrated Bone Marrow Aspirate in Lumbar Fusion. Ajiboye RM1, Eckardt MAI, Hamamoto JT1, Plotkin B1, Daubs MD2, Wang JC3.
7 Eur Spine J. 2015 Nov;24(11):2567-72. doi: 10.1007/s00586-015-4117-5. Epub 2015 Jul 14. Clinical and radiographic outcomes of concentrated bone marrow aspirate with allograft and demineralized bone matrix for posterolateral and interbody lumbar fusion in elderly patients. Ajiboye RM1, Hamamoto JT2, Eckardt MA2, Wang JC3.
8 J Orthop Res. 2011 Feb;29(2):173-80. doi: 10.1002/jor.21230. Epub 2010 Aug 25.Bridging the gap: bone marrow aspiration concentrate reduces autologous bone grafting in osseous defects. Jäger M1, Herten M, Fochtmann U, Fischer J, Hernigou ‘P, Zilkens C, Hendrich C, Krauspe R.
9 Orthop Rev (Pavia). 2009 Oct 10;1(2):e32. doi: 10.4081/or.2009.e32. Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients. Hendrich C1, Franz E, Waertel G, Krebs R, Jäger M.
10 Stem Cells International Volume 2016 (2016), Article ID 3908389 Multipotent Mesenchymal Stem Cell Treatment for Discogenic Low Back Pain and Disc Degeneration. Jeffrey Zeckser,1 Michael Wolff,1 Jason Tucker,2 and Josh Goodwin3
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